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Does CBD help or hinder sleep

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Does Cannabis Help or Hinder Sleep

Who doesn’t like a good night sleep? It is quite difficult for one to function without sleep in today’s stressful, fast- paced world. However, these are the very factors that often lead to people not getting enough sleep. For conditions like sleep apnea, insomnia, narcolepsy, etc. people are often prescribed over the counter medicines for instant relief. These medications; however, may have serious side effects on the patients. Due to this, many consumers try to explore medical cannabis as a potential sleep aid. Through this article, we would discuss whether Cannabis helps or hinders sleep.

CBD and sleep

CBD has become popular in the medical field, wherein, individuals are consuming it to treat a number of ailments, including insomnia. Due to this sudden increase in its popularity, a number of ongoing clinical and preclinical studies are trying to find whether CBD can help with various disorders. However, there are limited studies are centered on CBD and sleep.

A recent Consumer Reports survey that was conducted on CBD reported that 10% of its respondents were consuming CBD as a sleep aid. Most of them assured that it worked, however, the evidence is anecdotal. It is important for controlled studies to be conducted in order to gain some conclusive evidence about whether CBD really induces sleep.

High CBD strains often contain a terpene called myrcene. This terpene is said to have sedating effects. Therefore, myrcene has been used as a sleep aid since centuries. However, myrcene is found in several other plants apart from cannabis, such as hops. Therefore, researchers are unsure whether it is the myrcene in the CBD rich strains that helps people sleep or whether it is CBD itself. However, it can be noted that CBD is not generally consumed in a vaporized form, and therefore, does not contain much myrcene.

Another research conducted in 2017 extensive literature review titled: Cannabis, Cannabinoids, and Sleep: a Review of the Literature, studies the effects of CBD in conjunction with THC on sleep. It concluded that both can be used as sleep aids.

Consuming multiple cannabinoids at the same time might have mixed effects. THC has certain sedative-like effects on individuals. It has multiple properties that help individuals sleep, for instance, it helps people feel comfortable while being able to remain still. This is called catalepsy. CBD, on the other hand, does not alter the consciousness of individuals like THC. As a result, it is difficult to ascertain whether CBD alone can act as a sleep aid.

Dosage

A Preliminary study showed that CBD doses ranging from 75 to 300 mg helped patients sleep. In one particular case, high dose CBD also helped a PTSD patient. Since CBD does not have any psychedelic properties, it is safe to consume higher doses of it for optimum effects. A study held in 2018 administered doses of 1500, 3000, and 6000 mg to healthy subjects for six days. It concluded that CBD was safe to be consumed at higher dosages.

Conclusion

Through the aforementioned argument, it can be assessed whether CBD helps or hinders sleep. It should be noted that CBD’s effect on sleep requires a great deal of further research. Despite the fact that CBD seems to help patients sleep, its effects are subjective and differ from person to person. It is a great alternative for those who wish to use a product with no side-effects. Additionally, CBD is worth exploring for those who want to avail the benefit of marijuana without the psychedelic effects of THC. If you have trouble sleeping, you can consult your medical practitioner before using CBD for your condition. We strongly advise against self-medication.

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Kameshwar Modaka: An ideal formulation for chronic IBS (GRAHANI)

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Kameshwar Modaka for IBS

Abstract: Irritable Bowel Syndrome is a burden to both patients and the healthcare system as it requires high-cost medicines, frequent clinical visits, disturbed personal and professional schedule, anxiety, and depression in the patient. This chronic disorder causes abdominal pain or discomfort and is characterized by abnormal defecation that presents mainly as either constipation or diarrhea symptoms.  There is no standard allopathic treatment available for such a complex condition; the plan of treatment differs from person to person, doctor to doctor. 

In such a situation most patients turn to Ayurveda that describes this disorder as “GRAHANI” in its texts as it offers a promising treatment for patients suffering from IBS and improves his/her quality of life. Kameshwar Modaka is one such miraculous formulation that has been long lost in the Ayurveda texts. This study highlights the use of Kameshwara Modaka in the treatment of Chronic IBS (GRAHANI) and also proves how it can be the ideal formulation of choice for GRAHANI treatment.  

This is a case of a 32-year-old female with a history of mixed constipation and diarrhea bowel pattern for the last few years and how Kameshwar Modaka helped her overcome her complaints gradually.

Ayurveda Perspective 

According to Ayurveda, Grahani is a disorder that affects our Majjadhara and Pittadhara Kala. An ideal formulation for the treatment of Grahani would be having the properties of being ‘Grahi’ ‘Deepana’  ‘Pachak’. The Vijaya in the Kameshwar Modaka reassesses the inner dialogue in the affected person and induces calm and peaceful sleep. Which in turn helps to cure the ‘Mandagni’ cause due to mental stress. 

The formulation overall serves to give promising results in Grahani as it acts as AGNIVARDHAK and GRAHI for the physical impacts of the disease, and also the MEDHYA guna of cannabis helps the patient to overcome the mental disturbances he/she undergoes while having Grahani (IBS).

 Introduction

Irritable Bowel Syndrome is a common disorder that affects the intestine. Signs and symptoms include episodes of unexplained constipation and diarrhea, abdominal pain and cramping, bloating, etc. It is a chronic condition that one needs to manage in long term. 

The cause of IBS isn’t well understood. A diagnosis is often made based on symptoms. Moreover, there is no test to definitively diagnose IBS either. This makes the diagnosis and management of the disease an arduous task for healthcare professionals. 

IBS affects an individual physically as well as mentally as it refrains you from doing even the easiest things on the schedule as you never know when the complaints kick in.

Case Report

Today Vaidyas prescribe Kameshwar Modak in the treatment of Sexual Dysfunction and it has gained popularity in that field due to its promising and instantaneous results.  A very few of us know that Kameshwar Modak has been mentioned as a formulation that can be used in the effective treatment of GRAHANI roga and more analysis suggest that it can be an ideal drug for the treatment of GRAHANI.

Patient description

A 32-year-old female was presented with complaints with a history of mixed constipation and diarrhea bowel pattern. She reported that she ‘either can’t go or can’t stop going to the bathroom’. A few years ago (roughly 5 years) she complained of having long durations of constipations with lower abdominal pain but as time went by her symptoms progressed. The duration of constipation and intensity of pain gradually started to increase and it could turn worse with stress.

Case history

She was referred to a Gastroenterologist by a General Practitioner 2 years ago who did a full workup including blood testing and ultrasound examinations and also colonoscopy. All tests were unremarkable. She was diagnosed with IBS with constipation and started treatment with laxatives. 

Over the past year, she has developed intermittent diarrhea every 10 days and followed by a few days of constipation and complaints of having 3-5 episodes of watery or semi-formed stools.

Lately, she has been training and has had a sense of incomplete evacuation with lower abdominal cramping and bloating.  She has no celiac disease. She is moderately anxious.

Dietary & Lifestyle Habits

The patient has been eating healthy food but the complaints persist no matter what she eats. She does not consume alcohol nor does she have any other ‘habits’. She has a good overall routine and makes sure she gets 8 hours of sleep.

Previous treatment 

She used milk of magnesia or Castor oil when she was constipated and used TAB LOMOTIL (Diphenoxylate and Atropine) on rare occasions when she had diarrhea. 

Treatment plan

Medicines to be used – Kameshwar Modaka. She was prescribed Kameshwar Modaka 250 mg every day after food sublingual.  She was also asked to make dietary modifications and practice Yoga (certain asanas) as a part of her daily routine. 

Expected outcome of the treatment plan

It was expected Kameshwar Modaka would be able to help the patient ‘manage her situation’ better with time. 

Actual outcome

As expected the patient got little relief within a week. She did not have an episode of constipation and she was less anxious overall.  She was keen to continue her treatment and felt hopeful for the first time during her treatment period of 2 years that her life would be close to normal again.

Discussion

The treatment was decided considering the mentions of Kameshwar Modaka as one of the treatment drugs for Grahani in the Ayurveda literature. 

Grahani Roga should be primarily treated for AGNIVARDHANA CHIKITSA with the help of drugs that have the quality of DEEPANA and PACHANA. Kameshwar Modak as a formulation has the aforementioned qualities and serves to be an ideal drug of choice for the treatment of GRAHANI. 

Conclusion

This case study shows that GRAHANI can be successfully managed with Kameshwar Modaka. It is supportive for further research, as Grahani Chikitsa is one of the most challenging chikitsa Vaidyas face even today!

Dr. Sameer Paranjpe, Consultant Ayuvedacharya

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Ayurveda has a solution for your Migraine

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Ayurveda has a solution for your migraine

Abstract: This case study demonstrates the use of Trailokya Vijaya Vati highlighting its main ingredient cannabis in the treatment or prophylaxis of Migraine. A Migraine is a strong headache that often comes with nausea, vomiting, and sensitivity to light and sound. It can last hours or days. It is a headache of varying intensity and can cause throbbing pain or a pulsating sensation in one particular area. The pain sometimes can be so severe that it interferes with your daily activities.

There is mounting evidence that the endocannabinoid system can directly reduce migraine pain when activated by naturally produced cannabinoids or medical cannabis taken by patients. Cannabis can help to reduce inflammation in the protective dura mater tissue covering the brain and minimize the release of pro-inflammatory substances, both of which contribute to the onset of a migraine. Also, there is a presence of cannabinoid receptors in the brain. These receptors interact with the cannabinoids in the formulation and help to strengthen the body’s ability to reduce pain sensation.

This is a case of a 35 yr old female with a history of Migraines for the last 20yrs (since she was 15-16 yrs old). She has been taking anti migraine medicine every time she has had an attack for relief. Her migraines have changed in nature (intensity has fluctuated) over the last 20 years. In her teens, they were at their worst. She used to panic, her professors in college didn’t really understand the severity of it and often would think that she was trying to get out of the class. She was often misunderstood. After trying out many medicines available in the market for her migraines she decided to opt for Ayurveda / Herbal remedy for her sufferings.

Ayurveda Perspective

According to Ayurveda, migraine is termed ARDHAVABHEDAKA and is mainly caused due to imbalance of VATA DOSHA. The increased VATA DOSHA hence causes SHOOLA. The most defining symptom is ARDHASHIRSHA VEDANA meaning pain in half the region of the head.

Vijaya is having Tikta Rasa Ushna Virya it has laghu Tiksnha Guna and Katu Vipaka. Hence it pacifies the Vata Dosha and helps in the treatment of any kind of SHOOLA. The VATASHAMANA action of Vijaya eases the migraine and the sedative action helps the patient with substantial rest required after a triggered panic.

Introduction

For those who regularly experience migraines, life carries unique challenges. Absolutely harmless sensory stimuli like bright lights, strong fragrances, or loud noises can trigger unbearable pain. Stress or even jet lag can set a crippling migraine in motion too! This agonizing pain can be accompanied by a loss of sensation, nausea, or alarming visual changes. The disruption associated with chronic migraines can be so persistent it can even erode one’s sense of self.

Although drugs commonly prescribed for the prevention and treatment of migraines help some individuals, they don’t offer relief for all the ones suffering from migraine! Similar to many heavy-hitting medicines, a host of unwanted side effects may evolve with use. However, the evidence is accumulating that Cannabis may be an effective treatment for migraines and chronic headaches.

Case Report

Patient description

This is a case of a 35 yr old female with a history of Migraines for the last 20yrs (from since she was 15-16 yrs old). She has been taking anti migraine medicine every time she has had an attack for relief. Her migraines have changed in nature (intensity has fluctuated) over the last 20 years.

Case history

She has had migraines for the last 20 years. The frequency of migraines was more in her teens and gradually decreased and she could go for months without an attack. But in the past 1 year, the frequency of attacks has increased to a minimum of 1 attack per week. For her the worst aspect of migraines has been their unpredictability – “One moment you could be cycling down the street, the next, I can’t see!” she described. She has had aura symptoms and is unable to tolerate light and sound when she had an attack. This was having a huge impact on her professional and personal life. She has been prescribed almost every medicine available in the market from sumatriptan to almotripan to zolmitirpan and even combinations.

Physical examination results

She was brought by her husband just after she got a migraine attack which was the third attack in the last 10 days. She was unable to open her eyes fully and insist on the doctor to speak in a low voice. She was unable to understand the questions asked to her and was dizzy.

Treatment plan

Medicines to be used – Trailokya Vijaya Vati . She was prescribed Trailokya Vijaya Vati only when she would feel migraine-like symptoms were aggravating. She was also asked to keep a tap on the factors that were aggravating her migraines. 1 tablet was to be taken when she would experience even mild headaches for the next month and then only when there is a pulsating or throbbing headache or other likely symptoms.

Expected outcome

It was expected not immediately but over time that the patient would find relief with her migraines and also that frequency of the migraines would decrease gradually.

Actual outcome

The patient came for a follow up after 15 days. There was an improvement in her symptoms. There was a significant reduction in the frequency of attacks and the duration of pain. She took a tablet every time she left even the mildest of the symptoms and would feel relieved within 15-20 minutes of taking the tablet. She has been sleeping well and was not feeling panicky anymore.

Discussion

The treatment was decided on the basis of the predominance of VATA DOSHA involvement. The Vijaya as mentioned has anti-inflammatory properties and is also an effective VATASHAMANA herb. It helps in reducing the pain gradually. The VATASHAMANA action of Vijaya eases the migraine and the sedative action helps the patient with substantial rest required after a triggered panic.

Conclusion

This case study shows that Migraine can be successfully managed with Trailokya Vijaya Vati. While science is supporting the use of Cannabis (Vijaya) in the treatment of migraines, practical knowledge regarding how – how much, and when to dose still requires further research.

Case Study shared by Dr. Radhika Mohite, Consultant Ayurvedacharya Published by HempStreet

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Trailokya Vijaya Vati: A solution for multiple ailments

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Trailokya Vijaya Vati

Abstract: This review summarizes the evidence for the use of Trailokya Vijaya Vati in the Pain encountered in Ureteric Calculi with Hydronephrosis and indigestion.

Stones can cause splitting pain in our bodies. A lot of people suffer from stones and the condition affects a number of people every year due to our unhealthy and improper diet. Research says that 1 out of 10 Indians will experience having a Stone in their lifetime. As far as the stone is in the kidney there are certain complaints, but definitely not alarming.

The real set of complaints arise when the stone starts to pass from the kidney downwards out of the urinary tract. Passing a stone can be very very painful. Small stones may form and pass on their own without causing any symptoms. However, most medium and large stones are extremely painful to pass and require medical attention, especially for pain management.

Indigestion occurs when stomach acid comes in contact with the sensitive and protective lining of the digestive system. The stomach acid breaks down the lining leading to irritation and inflammation which can be very painful.

Patient Details

Patient 1 – This is a case of a 35 yr old male with complaints of ‘jumping pain’ in his lower abdomen radiating towards the groin. He was apparently alright till morning and started experiencing this pain after traveling (for about 50 km). USG suggested that it was ureteric Calculi about 8.4 mm in left ureter.

Patient 2 – A 26 yr old female with the complaint was brought by her husband who complained of indigestion and burning pain in her chest, pain in the back and abdomen. She was vomiting food and water when ingested. She required immediate pain relief.

Introduction

Pain is the alarm of the underlying diseases. A symptom that announces that something is wrong with our body. Today, pain management in various conditions or diseases is a newer concept with an approach to managing only and only pain in the list of complaints to give a feeling of ‘being alright’ to the patient and gradually treat the condition without disturbing his/her routine.

Medical Cannabis is an increasingly popular alternative against opioids, other traditional drugs, or even against modern medicine.

How does Cannabis work in Pain Management?

The Cannabidiol (a component of Cannabis) stimulates the brain’s cannabinoid receptors and reduces inflammation and pain levels.

Side effects of Medical Marijuana use are minimal especially as compared to opioids or modern medicines and they as not as addictive as opioids as well. Over years, Cannabis has shown significant promising results in pain management.

Case Report (Patient 1)

Patient description

This is a case of a 35 yr old male with complaints of ‘jumping pain’ in his lower abdomen radiating towards the groin. He seemed to be apparently alright till morning and started experiencing this pain after traveling (for about 50 km).

Case history

USG was done immediately which showed Left Ureteric Stone 8.4 mm with Hydronephrosis. The patient was a healthy individual with no co-morbidities.

Physical examination results

The gait of the patient was antalgic and he was restless. He represented typical loin to groin pain.

Treatment plan

Medicines used – Trailokya Vijaya Vati. He was prescribed Trailokya Vijaya Vati SOS after the onset of pain, as he insisted on pain relief as a primary expectation. He has also prescribed medicines for the management of Ureteric Calculi.

Expected outcome of the treatment plan

Immediate pain management.

Actual outcome

The patient rested in the clinic until she was free from pain. She was advised to rest and opt for LAGHU AAHAR. After about 30 mins of ingestion, the patient felt relief from pain.

Discussion

Pain management was the only target outcome of the treatment. But in the case of indigestion, Trailokya Vijaya Vati served both the purposes

  • Pain management
  • Disease management due to its VATAGHNA, DEEPANA, PACHANA, and AGNI VARDHANA properties

Conclusion

As evident from the above case, nature is the best combinatorial chemist and has possible answers to all diseases for mankind. Medicinal plants and their formulations especially Cannabis formulations play a vital role in pain management with minimal, easily manageable, and reversible side effects. Modern medicines give results but come with undesirable side effects that may sometimes cause permanent damage to an organ or a system. To increase the acceptability and awareness amongst the people regarding herbal formulations there is a need for plenteous research.

Case study shared by Dr. Neeraj Kamathe, Consultant Ayuvedacharya

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