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How long does THC stay in the system?

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How long does THC remain in our body

Marijuana, still in the process of establishing and justifying it’s identity in the society, otherwise known as weed, cannabis, among several other synonyms, is the most widely tested for substance, be it athletes or criminals. While hemp and industrial hemp as well as other cannabis based products have negligible quantity of THC, loose marijuana leaves, most widely used form of marijuana, consumed by marijuana smokers, mostly contains significant amount of the cannabinoid, THC in it. THC, or tetrahydrocannabinol, is one of the primary and recognised constituent of marijuana, known for it’s psychoactive properties. While hemp is a certified industrial raw material, cannabis is well-known for it’s medicinal properties, marijuana is prevalently used for recreational purposes and called out as recreational marijuana. This has caused even the employers to conduct tests prior to offering jobs. These tests have thus kept marijuana consumers on their toes.

This article will shed a light on the means through which THC enters the body and travel through it, the factors that affect detection of marijuana in the body and the various kind of tests conducted to detect the period of consumption. For everyone who is expecting to undergo a drug-test in the near future, this article will help you to understand the working of THC in the body and how these drug-tests are influenced by miniscule factors, such as metabolism and body mass index(BMI), which are in turn shaped by one’s age and daily activities.

How does THC spread though the body?

Different marijuana strains have differing level of THC as their constituent. However, all the strains have similar method of blending in the body of the consumer. THC, primarily acts on CB1 receptors, largely present in the brain and in other parts of the body as well as in the central nervous system. It also acts, in a diminished manner, on the CB2 receptors, on spleen and liver. When marijuana is either smoked or vaporized, the THC in the marijuana enters the bloodstream through the lungs, following which it reaches the various receptors present throughout the body and binds to them, as the blood flows through the body. When THC is ingested, even though the course of spread is same, the action time on the body is a little longer.

THC, is characterised as lipid soluble, that is, it readily dissipates in the lipids and fats present in the body. Hence, they accumulate on the fat tissues, which tend to stay in the body for a long time. As the THC gets moved through the body in the bloodstream, it gets broken down by the liver and produces metabolite called, 11-OH-THC, which is further metabolised to the inactive THCCOOH, which is primarily screened for in the drug tests. THC, solely, is easily broken down and hence, leaves the body. These metabolites, however, stored in the adipose fat tissues, stay for a longer duration in the body, as they cannot be easily broken down. 

Factors impacting detection time

  1. Metabolism: Refers to the time taken by the body system to break down the active substance of marijuana, i.e, THC, which differs from person to person depending on the kind of activities people indulge in, such as physical activities. These activities, in turn, also differ on the basis of age. More activities lead to THC exiting the body sooner, making body fat also a determinant.
  2. Frequency of use: For chronic users, THC remains in the body for upto 70 days. Moderate users can pass a drug test after 15-20 days. While occassional users can easily pass a drug test after 7 -10 days. However, it also depends on which method of testing is applied as well on the level of tolerance developed by the user.
  3. Dosage: The higher amount of THC consumed, the longer time the body system will require to break it down. The method of consumption also generates difference in the length of time THC stays in the body.
  4. Genetics:  CYP2C9 and CYP3A4 are two enzymes which are genetically variant and are involved in the mechanism of. Thus, depending on the presence of either enzyme, metabolism is either slow or fast.  
  5. Fluid intake: Dehydration causes the concentration of THC in blood to rise.

Tests for marijauna detection

Data released by the U.S. National Drug Court Institute establishes four major ways of detecting marijuana in one’s system. Four of them are as follows:

  1. Saliva Test: This test is used for detection of use of marijuana in the immediate past, i.e, few hours to 1 day, maximum 2 days.
  2. Blood test: Has similar potency as blood test.
  3. Urine Test: Most common method of testing. Can detect marijuana several days after last use. For chronic user, this extends to 8-9 weeks as well.
  4. Hair test: Not the most trusted method, as most results are false-positive. This happens due to the traces that remain in the hair follicles, when you are around people who smoke.

There exists quantitative as well as qualitative detection tests. While qualitative test checks for the presence of substance in the body, quantitative tests is more rigorous and sensitive. Quantitative tests check for the precise amount of substance in the body.

Word from HempStreet

As marijuana legalisation is still underway, it is important to be aware of the associated conditions and characteritics of a drug test. While there have been various queries on how to pass this test, the only reliable way is through speeding up the metabolism as well as keeping in mind, the gap between when the substance was used last and the day when the drug test is taken.

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Synonyms and meanings of Cannabis in Ayurveda

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Synonyms and meanings of Cannabis in Ayurveda

What lies in the name? Well, it does, and this question becomes redundant when something or someone has scores of names to describe their functions. The functions of the subject what it does or effects on the object. The ancient Indian literature and mythology shares on record the myriads of names from Lord Shiva to Rama and from Krishna to Lord Dhanwantri if we mainly talk about Ayurveda. 

The reason for giving these lords numerous names is to describe their powers in their names.

Any subject or object of some importance carries synonyms, and more are the names, more is the importance it holds. Let us specifically discuss the case of Cannabis here. This plant might have attracted people from the western world in the 20th century, but its significance lies in Ayurveda literature since time immemorial. From ‘Sharangdhar Samhita to ‘Rasendra Sara Sangraha, and from ‘Bhavpraskahs to Rasendra Chintamani’ a total of 34 different names have been given in these ancient works of literature.

The synonyms carry the meaning and convey the functions that ‘Cannabis’ does in the body or mind. So, let us discuss some of the synonyms of Cannabis and their meanings/utilities that can enable you to learn and know about the wonder herb.

  1. Sivaluli– ‘Bhanga’ or Cannabis is known to be originated from Lord Shiva himself and therefore has been used in Shiva Poojan along with leaves of Indian bel. The offering of the leaves on ‘Shiv-Lingam’ shows the significance the herb carries.
  2. Vijaya– Cannabis is called ‘Vijaya’ as it can give you victory over the six desires of the mind.
  3. Bhangi– Cannabis is called ‘Bhangi’ as it treats ‘Taapa traya’ which is referred to 3 basic types of diseases, namely adhyātmika, adhibhautika, adhidaivika.
  4. Ganja– Ganja is one of the oldest and common names of Cannabis Sativa. It is dried leaves of Cannabis Sativa and called ‘Hemp’ in English. Since it has the properties to intoxicate like alcohol, it is called Ganja.
  5. Vimrardini– ‘Vimradan’ in Sanskrit means pressing and squeezing, the Swaras or Juice of ‘Bhanga’ made with this pressing; hence, it is given this name.
  6. Divya– Cannabis is called as ‘Divya’ as the judicious use of ‘Bhanga’ gives exhilaration and pleasure.
  7. Siddha– ‘Cannabis’ is said to be a holy herb as it has been used as a sacrament and its usage in almost every known and unknown mind and body diseases.
  8. Siddida– Cannabis bestows enlightenment as even in the modern-day ‘Naga’ sadhus have been found using it for doing the practice of the hardest ‘Hatha’ yoga. The toughest form of ‘Yoga’ which requires practice with perseverance.
  9. Siddha muli– An ascetic is a person who follows the pursuit of contemplative ideals and practices extreme self-denial or self-mortification for religious reasons. The cannabis plant does not require any efforts for its cultivation, and like a person who leads an austerely simple life, it grows humbly and only at its own.
  10. Manonmai– Cannabis accomplishes in winning over the problems of the mind.
  11. Madhu Drava– The consumption of Cannabis stimulates ‘Sudha Drava’ or happy hormones such as dopamine in the brain and gives a state of happiness.
  12. Pasupasavinasini– Cannabis restores health from non-human behaviour.
  13. Kalaghni– Under acute conditions like severe pain, acute abdomen, and cholera, the use of Cannabis has shown patients recovering from these conditions which make its name as ‘Kalaghni’ or victory from death quite apt.
  14. Sarvarogaghni– Cannabis is used in two hundred Ayurveda formulation, and its usage is mentioned in almost every disease that it is rightly being referred to as ‘Sarvarogaghni’ or a cure for diseases.
  15. Chidahlaada– Cannabis is called as ‘Chidahlaada’ as it has been used to give happiness and joy at every festive occasion.

Cannabis is the herb which has been used by Vaidyas, Rishis and ordinary citizens since times immemorial before it received a bad name and a taboo in the early 20th century. If we closely study its names and references from where it got its various names and shun the sceptical view to allow more scientific studies on it. The chances are there the world would accept Cannabis as the herbal medicinal plant, not as a roadside harmful and redundant grass.

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Tips to Buy the Best CBD Oil

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CBD OIL

As the popularity of medicinal cannabis grows, a number of people are substituting their medication with cannabis products. CBD or cannabidiol, a compound found in cannabis, is gaining popularity in today’s medical field due to its multiple benefits. Not only does CBD help treat certain ailments, it helps better the lifestyle of individuals as well. Do you wish to buy CBD oil? Are you unsure about where and how you should buy it? Well, then you’ve come to the right place for information. Here are some tips to buy the best CBD oil.

About CBD and CBD oil

CBD is one of the major compounds present in marijuana. This compound is well known for its therapeutic benefits. CBD helps lower anxiety, alleviates pain, overcome nervousness, reduces inflammation, etc. Unlike THC or tetrahydracannabinol, another dominant compound found in cannabis, CBD does not possess any psychoactive properties and thus, does not make consumers high. Due to its multiple benefits, CBD oil is available in the market and is in high demand. CBD oil helps ease symptoms related to conditions such as epilepsy, anxiety, cancer, PTSD, etc.

Why you should be careful while purchasing CBD oil

Today, there are countless brands and product lines selling CBD products such as CBD oil. This makes it confusing for the buyers as to which products are worth buying. Sadly, all the products available in the market are not equally good, and it isn’t easy to be able to tell the good products from the bad ones.

A number of CBD oils and products available online are low-quality, and some are even fake. Some of these products contain THC, and some have toxic chemicals which can cause severe poisoning. Therefore, it is important to follow certain guidelines in order to select the best CBD oil before buying.

Tips for buying CBD oil

Here are some tips to help you buy the best CBD oil.

  1. Note the ingredients: One should always read the ingredients of the product and compare them with those of the other products available. For instance, some good quality CBD oils would include additional ingredients such as melatonin or MCT oils that provide more benefits to individuals. On the other hand, low quality oils would have harmful ingredients like vegetable glycerin and propylene. Therefore you should be on the lookout for the aforementioned components that could prove whether a product is good or bad.
  2. Check the THC content: Prior to buying the product, you should check the laws regarding CBD or CBD oil that apply in your state. Most of the states impose restrictions on the amount of THC that should be present in CBD oils. In a good quality effective oil, the THC concentration should be 0.3% or lower than that. Not only does a higher THC content limit the benefits of the oil, it can potentially be categorized as recreational marijuana.
  3. Google the brand and check reviews: It is necessary for you to google the brand name before buying the oil. Check whether the website seems legitimate enough. You should also check the reviews from other customers in order to analyze whether the product is good or not. Sometimes, there can be fake reviews as well; therefore, only trusted bloggers’ reviews should be considered. This step would help narrow down your choices along with the other tips.
  4. Check lab reports: It is essential to check whether a laboratory has tested the CBD oil. If the product has successful lab results, the information regarding that should be available on the brand’s website. An absence of lab reports could suggest that the product is suspicious. In the reports, it should be noted whether the laboratory is a known one or not, and whether the products are accredited with following the International Organizations for Standardization (ISO). It should also be checked if the reports were published less than 3 years ago, since they would be considered expired after that.
  5. Choose within your budget: Once you have checked for all of the above conditions and narrowed down your list of oils, you can choose the one that is within your budget. Sometimes, certain products are priced high because of their trendy packaging or outer looks, therefore you can cut the cost by choosing another oil with the same ingredients and a less attractive packaging.

Word from Hempsteet

Discussed above, are some important tips for buying the best CBD oil. If you think CBD oil could benefit you, it is recommended that you contact your medical health professional and get a prescription for the same. We advise against self-medication using cannabis.

References:

medium.com/alphagreen/how-to-buy-cbd-products-online-and-benefit-10-tips-to-remember-5df4de0e7094

www.healthline.com/health/best-cbd-oil

cbdoilreview.org/cbd-cannabidiol/cbd-oil-product-buying-tips/

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Cannabis and Ulcerative Colitis

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Cannabis

Ulcerative Colitis (UC) is a disease of the inflammatory bowel that causes inflammation and ulcers in the digestive tract. In Ulcerative Colitis, the innermost lining of the intestine (colon) is affected. This disease affects the gastrointestinal tract and has a relapsing nature.

The symptoms of UC can be diarrhea, an urgency to defecate, abdominal pain, rectal pain, blood in the stool, fever, fatigue, weight loss, malnutrition, dehydration, etc. Severity of the inflammation can lead to serious health complications like increased risk of colon cancer, bleeding, bone loss, hole in the colon, etc. Though there is no exact reason for Ulcerative Colitis to happen, it is suspected to develop due to factors such as immune disorder, genetics, bacteria or viruses can spark the immune system, etc.

UC can be diagnosed with the help of different tests like colonoscopy, endoscopy, biopsy, stool test, etc. UC can be of different types like proctosigmoiditis, ulcerative proctitis, left-sided colitis, pancolitis, and acute severe ulcerative colitis. There is no permanent cure for UC, but treatment can reduce symptoms and can bring long-term remission and prevents relapses.

UC or Pittaj Grahani in Ayurveda is a disease of purisha vaha srotas which is caused by Pitta Pradhana Vata doshas. Ayurveda works on the philosophy of doshas, Vata, Pitta, Kapha, any imbalance in the doshas creates health issues in one’s body. As per Ayurveda, treatment involves Shamana chikitsa (internal medicines), Shodana chikitsa (Panchakarma therapy), lifestyle modifications and stringent diet regime. In more severe case, Panchakarma therapy plays a vital role as it quickly detoxifies & rejuvenates the digestive system, controls the inflammation, rectal bleeding and heals the ulcerations.Past analysis has shown that by getting Ayurvedic treatment, patients can avoid the colon surgery. 

UC can be treated with a combination of treatment, i.e. diet, medication or in severe cases surgery. We’ll look at each of the treatments separately:

•    Diet

It is suggested that one suffering from UC should take low fibre and low-fat diet, the idea is to eat healthy and light, the fat will avoid flaring up the colon and fibre will reduce the number of stools one passes. One should have a good amount of fruits and vegetables and a diet that feeds ample nutrients and vitamins. Some medical practitioners may advise stopping the intake of dairy products if one is lactose intolerant.

There are some home remedies to treat UC; one can have probiotics that are filled with healthy bacteria avoiding inflammation. One can use turmeric in daily cooking; turmeric is an age-old herb that has antioxidant properties.

•    Medication

Various kinds of medicines are being used to treat UC that leads to controlling the symptoms. The medicines may include antibiotics.

•    Surgery

In severe case of UC, the patient has to undergo surgery; the surgery might involve the removal of the colon and the rectum. Due to the advancement of medical technology, an internal pouch is created and is linked to the anus, avoiding ileostomy.

Cannabis and Ulcerative Colitis

In some of the studies, cannabis has shown signs of decreased inflammation and maintain remission of the condition, so usage of cannabis to treat symptoms of UC such as abdominal pain, nausea, diarrhea, etc. might be helpful.

A professor of microbiology and physiological systems at the University of Massachusetts Medical School in Worcester researched how cannabis stops inflammation.

They started the research by acknowledging an already known inflammation process that occurs when the body is infected with a pathogen. The neutrophil influx is a normal reaction of the immune system that sends neutrophils a type of white blood cell to fight against foreign microorganisms such as viruses or bacteria.

However, if the immune cells react disproportionately, they can also destroy the epithelium, which is the protective layer of cells that lines the inside of the intestine. So, to stop the overreaction of the immune response, particular molecules are “dispatched” and transported across the epithelium to stop the inflammation.

It was found that the second process requires endogenous cannabinoids (endocannabinoids), which are naturally produced by our bodies and have a similar effect to the cannabinoids in cannabis.

By performing experiments in mice and human cell lines, the team found that if endocannabinoids are lacking or are insufficient, the body cannot control the inflammation process anymore and the neutrophils attack the protective intestinal layer.  The scientists believe that cannabis makes up for the natural cannabinoids, inducing the same anti-inflammatory effect that endocannabinoids would have.

To conclude, all the arguments, discussion, debates reach one point, i.e. whether the studies that have been conducted are enough to consider the usage of medical cannabis to treat any ailment. Can one overlook the side effects of cannabis? It is always advisable to consult a medical practitioner before using cannabis to treat any illness.  And it is also vital for the medical practitioner to be well informed about medical cannabis and the studies available on it, to advise patients accordingly.


[1] https://charaka.org/ulcerative-colitis/

[2] https://www.medicalnewstoday.com/articles/322764#How-cannabinoids-stop-the-inflammation

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